Bioactive Compound and Antioxidant Activity of Balelo Sea Snail (Conomurex sp.)

Abstract

Molluscs have great potential to developed as a new candidate of antioxidant source in the pharmaceutical and nutraceutical field. This study aims to investigate the bioactive compound and antioxidant activity of balelo sea snail (Conomurex sp.) from Derawan island, East Kalimantan. Extraction of balelo sea snail was carried out using three types of solvents, such as methanol, ethanol, and ethyl acetate. The analysis consisted of yield, chemical composition, bioactive compounds and antioxidant activity using DPPH. Balelo sea snail had 27.30% of protein content, 2.00% of ash, 10.30% of lipid, and 4.11% of carbohydrate. The yield of balelo sea snail meat was 34.7%, and the yield of methanol, ethanol and ethyl acetate extract were 15.33%, 15.16% and 0.89%, respectively. Balelo sea snails contain alkaloid, tannins, saponins, phenol hydroquinone and steroids. The antioxidants activity of extract methanol and ethanol of balelo sea snail (IC50) correspondingly were 1055, 8 µg/mL and 1165.9 µg/mL. Balelo sea snail is potential as an antioxidant source and has bioactive compound that can be develop in the pharmaceutical and nutraceutical field.