Are Pediatric Cancer Patients a Risk Group for Vitamin D Deficiency? A Systematic Review

Abstract

Vitamin D plays a vital role in supporting healthy growth and development. Deficiency in this nutrient has been associated with various health problems, including an increased susceptibility to infections and other complications, particularly in vulnerable populations. Pediatric cancer patients are at a greater risk of vitamin D deficiency due to combined effects of illness, treatments, days of hospitalization, and ongoing developmental needs. This study reviewed the medical literature to understand how common vitamin D deficiency is in this type of patient and its potential impact on treatment outcomes, trying to conclude whether they are a risk group for vitamin D impairment. These findings highlight the importance of checking vitamin D levels at diagnosis and throughout treatment, alongside providing supplements when needed, to support better treatment responses and overall health in pediatric oncology patients.