Abstract
The ethyl acetate fraction of butterfly pea flower was found to have higher antioxidant activity than other fractions. This fraction can be utilized in making gel mask preparations, as an alternative to topical antioxidants. The purpose of this study was to formulate the ethyl acetate fraction in a gel mask preparation, and test the physical characteristics and stability of antioxidant activity before and after being stored for 3 months at room temperature. Extraction of telang flowers, using 70% ethanol, followed by fractionation with n-hexane, ethyl acetate and water. The results of the ethyl acetate fraction were tested for antioxidant activity, then formulated in a gel mask preparation. Evaluation of the physical characteristics of the preparation includes organoleptic test, homogeneity, pH, viscosity, adhesion, spreadability, and antioxidant activity test, before and after 3 months storage with DPPH. The results of the antioxidant activity test of the ethyl acetate fraction obtained a value of 25.14 µg/mL. The results of the physical characteristics of the gel have a pH 5.18 ± 0.035, viscosity 9541 ± 32.14 cps, adhesion 2.04 ± 0.015 seconds, spreadability 4.55 ± 0.015 cm. The antioxidant activity of the gel decreased after storage for 3 months.Fraksi etil asetat bunga telang ditemukan memiliki aktivitas antioksidan lebih tinggi dibanding fraksi lainnya. Fraksi ini dapat dimanfaatkan pada pembuatan sediaan gel mask, sebagai alternatif antioksidan topikal. Tujuan penelitian ini untuk memformulasi fraksi etil asetat ekstrak bunga telang dalam sediaan gel mask, dan menguji karakteristik fisik serta stabilitas aktifitas antiokisidan sebelum dan sesudah disimpan selama 3 bulan pada suhu ruang. Ekstraksi bunga telang, menggunakan etanol 70%, selanjutnya fraksinasi dengan n-heksan, etil asetat dan air. Hasil fraksi etil asetat diuji aktivitas antioksidan, selanjutnya diformulasi dalam sediaan gel mask. Evaluasi karakteristik fisik sediaan meliputi uji organoleptis, homogenitas, pH, viskositas, daya lekat, daya sebar, serta uji aktivitas antioksidan, sebelum dan sesudah penyimpanan 3 bulan dengan DPPH. Hasil pengujian aktivitas antioksidan fraksi etil asetat diperoleh nilai sebesar 25,14 µg/mL. Hasil karakteristik fisik sediaan memiliki pH 5,18±0,035, viskositas 9541± 32,14 cps, daya lekat 2,04±0,015 detik, daya sebar 4,55 ±0,015 cm. Aktivitas antioksidan gel mask mengalami penurunan sesudah disimpan selama 3 bulan.
Cite
CITATION STYLE
Puspitasari, D. F., Utami, R. N. A., & Wildan, A. (2025). FORMULASI DAN UJI STABILITAS GEL MASK FRAKSI ETIL ASETAT BUNGA TELANG (Clitoria ternatea L.) SEBAGAI ANTIOKSIDAN. Jurnal Insan Farmasi Indonesia, 8(1), 46–57. https://doi.org/10.36387/jifi.v8i1.2423
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