Malignant mesothelioma after radiation treatment for Hodgkin lymphoma

51Citations
Citations of this article
34Readers
Mendeley users who have this article in their library.

Abstract

Malignant mesothelioma is a relatively uncommon malignancy. Although the pathogenesis is primarily related to asbestos, the disease may be associated with radiation exposure. Recently, increased risks for second primary mesothelioma after radiation for lymphoma have been reported. Because these findings are based on small numbers of patients, they need to be confirmed. We examined mesothelioma risk in 2567 5-year survivors of Hodgkin lymphoma. The risk was almost 30-fold increased in Hodgkin lymphoma patients treated with irradiation compared with the general population. Although histology and survival of the mesothelioma cases were comparable with cases from the general population, asbestos exposure and the proportion of males were lower than expected. The evidence for radiotherapy as cause for mesothelioma independent of exposure to asbestos is expanding, and the diagnosis of mesothelioma should be kept in mind whenever related symptoms arise in patients who had previous irradiation. © 2009 by The American Society of Hematology.

Cite

CITATION STYLE

APA

De Bruin, M. L., Burgers, J. A., Baas, P., Van’t Veer, M. B., Noordijk, E. M., Louwman, M. W. J., … Van Leeuwen, F. E. (2009). Malignant mesothelioma after radiation treatment for Hodgkin lymphoma. Blood, 113(16), 3679–3681. https://doi.org/10.1182/blood-2008-10-184705

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free