A withdrawal syndrome after abrupt discontinuation of alprazolam

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Abstract

A patient who received therapeutic doses of alprazolam for 8 weeks experienced a withdrawal syndrome beginning 18 hours after its abrupt discontinuation. Short-acting and minimally sedating benzodiazepines may have increased potential for withdrawal reactions.

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Noyes, R., Clancy, J., Coryell, W. H., Crowe, R. R., Chaudhry, D. R., & Domingo, D. V. (1985). A withdrawal syndrome after abrupt discontinuation of alprazolam. American Journal of Psychiatry, 142(1), 114–116. https://doi.org/10.1176/ajp.142.1.114

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