Inhibitory activity of α-Amylase and α-Glucosidase by padina pavonica extracts

Abstract

The objective of this study was to determine the potential of polyphenols and phlorotannins extract from Padina pavonica in inhibiting α-amylase and α-glucosidase. Total phenolic content of P. pavonica was 17.63±0.25 μg GAE/mg extract and total phlorotannins content was 1.94±0.19 μg PGE/mg extract. The results showed that polyphenols (IC50 = 0.36±0.05 mg mL-1) and phlorotannins (IC50 = 0.25±0.02 mg mL-1) can inhibit a-amylase, but lower than acarbose (EC50 = 0.06+0.00 mg mL-1). Polyphenols (IC50 = 26.57±2.08 mg mL-1) and phlorotannins