Prospects for para‐aortic irradiation in treatment of cancer of the cervix

Abstract

The incidence of para‐aortic node metastasis in cancer of the cervix ranges from 5% to 50% in clinical Stages I‐IV. Extended field irradiation is being administered more frequently because of the high incidence of extrapelvic disease. The cancer of the cervix material at Walter Reed General Hospital has been analyzed as to site and time of failure to determine who might have benefited from extended field irradiation. Of patients who fail, the majority will have uncontrolled pelvic disease regardless of other involvement. Diagnostic procedures including staging laparotomy are unable to predict pelvic failure or the presence of occult distant disease in lung and bone. The maximum number of patients who could benefit from para‐aortic irradiation is less than 3% of a total series. It is concluded that the salvage of patients with para‐aortic metastasis will be small, but for those few long‐term survivors, the benefit will be great. Copyright © 1975 American Cancer Society