This paper posits that the gene-centered viewpoint of the organism (gene-centrism) is not enough to explain biological complexity. Organisms are not completely determined by their genomes; rather, living beings can be seen as interpreters or intentional systems. Epigenetics is the framework that allows the avoidance of gene-centrism and permits the emergence of a more holistic standpoint where determination and novelty can coexist, as shown with examples taken from developmental biology and macromolecules folding. In summary, as P. Medawar and J. Medawar wrote: "Genetics proposes; epigenetics disposes".
CITATION STYLE
Burbano, H. A. (2006, January 24). Epigenetics and genetic determinism. Historia, Ciencias, Saude - Manguinhos. https://doi.org/10.1590/S0104-59702006000400004
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