A prospective hospital-based sentinel study conducted in Rio de Janeiro identified a shift in the pattern (long to short electropherotype and P(8) to P(4) genotype) of rotavirus strains recovered from children with severe diarrhea a few months after the far-reaching Brazilian rotavirus immunization program was launched, posing new interesting challenges.
Gouvea, V. S., Domingues, A. L. S., Naveca, F. G., Pedro, A. R., & Bevilacqua, C. C. (2008). Changing Epidemiology of Rotavirus-Related Hospitalizations in Rio De Janeiro, Brazil, from 2002 to 2006. The Open Virology Journal, 1(1), 47–50. https://doi.org/10.2174/1874357900701010047