Associação entre o perfil lipídico e medidas antropométricas indicadoras de adiposidade em adolescentes

Abstract

The aim of this study was to determine the association between lipid levels and overall and central obesity in adolescents. A cross-sectional, descriptive correlation study. A total of 127 pubescent subjects participated in the study, 71 girls (13.39 ± 1.81 years) and 56 boys (13.10 ± 1.97 years). Overall adiposity was evaluated based on body mass index (BMI) and central adiposity was measured by waist circumference (WC) according to age, gender and race. Total cholesterol (TC), high-density lipoprotein (HDL-C), low-density lipoprotein (LDL-C) and triglycerides (TG) were determined after a 12-hour overnight fast. The results were analyzed using the chi-square test and Pearson's correlation, with the level of significance set at p<0.05. Obese boys presented larger proportions of increased LDL-C (א2=8.283; p=0.016) and TG (א2=6.422; p=0.04) and reduced HDL-C (א2=11.036; p=0.004) than non-obese and overweight adolescents. However, TC was similar among groups. Obese girls presented lower HDL-C levels than non-obese and overweight girls (א2=7.468; p=0.02). No difference in LDL-C, TG or TC was observed between obese, overweight and non-obese girls. A positive association was observed between logn TG and logn BMI (r=0.215; p<0.001) and between logn TG and logn WC (r=0.210; p<0.001). A negative association was observed between logn HDL-C and logn BMI (r=-0.425; p<0.001) and between logn TG and logn WC (r=-0.365; p<0.001). This study demonstrated a higher proportion of reduced HDL-C levels and increased TG among obese adolescents compared to non-obese subjects. A moderate inverse association was observed between HDL-C and overall and central adiposity.