Abstract
This work encompasses together a number of diverse disciplines (physiology, biomechanics, fluid mechanics and simulation) in order to develop a predictive model of the behaviour of a prosthetic heart valve in vivo. The application of simulation, for the study of other cardiovascular problems, such as blood clotting is also discussed. A commercial, finite volume, computational fluid dynamics (CFD) code (ANSYS/CFX) is used for the 3D component of the model. This software provides technical options for advanced users which allow userspecific variables to be defined that will interact with the flow solver. Userdefined functions and junction boxes offer appropriate options to facilitate multi-physics and multi-scale complex applications. Our main goal is to present a 3D model using the internal features available in ANSYS/CFX coupled to a multiscale model of the left ventricle to address complex cardiovascular problems. © Springer-Verlag Berlin Heidelberg 2007.
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CITATION STYLE
Díaz-Zuccarini, V., Rafirou, D., Hose, D. R., Lawford, P. V., & Narracott, A. J. (2007). Multi-physics and multi-scale modelling in cardiovascular physiology: Advanced user methods for simulation of biological systems with ANSYS/CFX. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 4487 LNCS, pp. 794–801). Springer Verlag. https://doi.org/10.1007/978-3-540-72584-8_105
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