Testosterone replacement therapy for older men

Abstract

A review of the currently published data indicates that testosterone replacement therapy in older men may be advantageous in terms of improving bone mineral density, increasing muscle mass and strength, and, in some men, improving libido and mood. However, the long-term clinical significance of these effects is still uncertain, as larger and longer-term studies are needed. In the short term (up to 3 years), the adverse effects of testosterone replacement therapy in older men seem predictable and manageable, but the longer-term effects on target organs, such as the cardiovascular system and the prostate, are yet to be determined. Copyright © American Society of Andrology.