Amidoximes: Applications and methods of synthesis

Abstract

Amidoximes are an interesting class of compounds. They can serve as starting materials for the synthesis of valuable heterocyclic and other useful compounds. Their use as starting materials has enabled a wide range of applications in novel pharmaceuticals, antitumor agents, antimalarial agents, nitric oxide synthase (NOS) substrates, enhanced textile materials, synthetic polymers and chelating resins. Concerning the chemistry of amidoximes, during the last 22 years some new methodologies as well as improvements of previously reported reactions appeared in the literature. In this review is discussed the application and methods used for synthesis of amidoximes.