Effect of cerebral oxygen saturation on postoperative nausea and vomiting in female laparoscopic surgery patients

Abstract

Background: The purpose of this study was to investigate effect of cerebral oxygen saturation (SCTO 2) on postoperative nausea and vomiting (PONV) in female patients who underwent laparoscopic surgery. Methods: This study included 90 female patients who underwent laparoscopic surgery (60 cases of gynecological operations and 30 cases of gallbladder operations). All patients were allocated into 3 groups of 30 patients each: group A (gynecological laparoscopic surgery), group B (gynecological laparoscopic surgery with mannitol treatment) and group C (laparoscopic cholecystectomy surgery). Perioperative SCTO 2, mean blood flow velocity of vertebral artery (VM), vascular resistance index of vertebral artery (RI), and PONV (within 48hours after surgery) were investigated. Results: No differences in age, body weight, operation time, and hemoglobin levels were observed among the patients (P>.05). The SCTO 2 values for groups B and C were lower than those for group A in both brain hemispheres at T 4 and T 5 (P .05). The RI was higher in group C than in groups A and B at T 4 (P