Activity of cathelicidin peptides against Simkania negevensis

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The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptidesPG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28proved to be active at very low concentrations (1 to 0.1g/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100g/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested. Copyright © 2011 Manuela Donati et al.




Donati, M., Di Francesco, A., Di Paolo, M., Fiani, N., Benincasa, M., Gennaro, R., … Cevenini, R. (2011). Activity of cathelicidin peptides against Simkania negevensis. International Journal of Peptides, 2011.

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