A Copper-catalysed Facile Synthesis of Highly Functionalized Aryl Sulphones in Guanidinium IL(GIL) aided with Ultrasound

Abstract

Ultrasonication aided copper catalyzed facile synthesis of highly functionalized aryl sulphones has been demonstrated by employing aryl sulphonyl hydrazides as suitable substrates in excellent yields in short time. Various 1-aryltriazene derivatives were used as a coupling partner in the presence of a [TMG][CH3COO] IL without any base or additives. The potential for the recycling and reuse of IL was also explored. Similarly, we elaborated the reaction scope by synthesizing copper-catalyzed aryl sulphones aided by ultrasonication replacing aryltriazenes with aryl boronic acids as coupling partner in [TMG][CH3COO].