Abstract
A multivalent galactosyl carborane derivative 10 (dendritic glyco-borane, DGB) was synthesized and demonstrated as a potential cell-targeting agent in BNCT with HepG2 cells. DGB 10 improved the delivery of boron to HepG2 cells and neutron irradiation data show DGB 10 with ten-fold improvement at killing the HepG2 cells over BSH. © 2011 The Royal Society of Chemistry.
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CITATION STYLE
Lai, C. H., Lin, Y. C., Chou, F. I., Liang, C. F., Lin, E. W., Chuang, Y. J., & Lin, C. C. (2012). Design of multivalent galactosyl carborane as a targeting specific agent for potential application to boron neutron capture therapy. Chemical Communications, 48(4), 612–614. https://doi.org/10.1039/c1cc14447b
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