Association between obesity and glomerular filtration rate in a population with arterial hypertension

Abstract

Introduction: Obesity has consequences for the health system due to the association with morbidity and mortality and the effect on quality of life. At the individual level, obesity generates proteinuria and glomerulosclerosis that accelerate the decrease in glomerular filtration. Objective: To determine the association between obesity and glomerular filtration rate in a population with arterial hypertension. Methodology: A descriptive cross-sectional study that analyzed obesity and glomerular filtration in 3,197 patients with arterial hypertension from a first-level care institution. Medical records were reviewed obtaining sociodemographic and anthropometric variables, clinical parameters, and classification of chronic kidney disease. Results: The population had an average age of 64 years (SD 12.47), and the majority were female (70.58%). The prevalence of obesity grade I was (26.11%), grade II (9.63%) and grade III (4.56%). Obese had a median rate of glomerular filtration superior compared to non-obese, but this difference was observed only in stages I and grade II grade. Conclusion: There is an association between obesity and an increase in the glomerular filtration rate only in stages I and II. Abdominal circumference, uncontrolled blood pressure and LDL were variables that influence the average glomerular filtration rate, having a different behavior by degree of chronic kidney disease.