Rationale for the use of therapeutic and prophylactic complex to prevent intolerance to acrylates in patients with hyperfunction of the thyroid glands

Abstract

This investigation is devoted to the analysis of acrylic removable denture's effect on the mucous and hard tissues of the oral cavity of patients with hyperthyroidism and, also, to rationale for application the curative and prophylactic range of measures based on the preparation "Endonorm" for precaution of events of intolerance of patients with mentioned pathology. Morphological and functional changes in the thyroid gland affect the general state of the human body, including tissues of the oral cavity, and these impairments usually manifest by the early loss of teeth due to caries and periodontal diseases. Oral manifestations of thyrotoxicosis include increased susceptibility to caries, periodontal disease, enlargement of extraglandular thyroid tissue, maxillary or mandibular osteoporosis, accelerated teething, and burning mouth syndrome. This problem in such patients, in particular, those suffering from hyperfunction of the thyroid gland, should be resolved by means of complex medicinal therapy to increase resistance and reduce the level of body sensitization. "Endonorm" is a mixture of dry vegetable extracts of white cinquefoil, prepared according to special technology, the main active component of the product is Albinin. Purpose of studying the indicators of trypsin-like activity of mixed saliva in patients with hyperfunction of the thyroid gland, whose dentures were manufactured by standard compression method, and by using proposed therapeutic and prophylactic measures. After the applying of removable dentures was defined, the increase of saliva's enzyme activity on 17% as compared with indices, which was before the beginning of the prosthesis. It established that the proposed curative and prophylactic range of measures permits to prevent the risk of development of events of acrylate intolerance and to normalize the studied indices on 1 month after the prosthesis.