T cell dynamics and the response to HAART in a cohort of HIV-1-infected elite suppressors

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Abstract

Elite controllers or suppressors are untreated human immunodeficiency virus type 1 (HIV-1)-infected patients who maintain undetectable viral loads. In this study, we show that most elite suppressors do not experience significant changes in T cell counts over a 10-year period. Interestingly, treatment of an elite suppressor with highly active antiretroviral therapy (HAART) led to a marked decrease in immune activation. © 2009 by the Infectious Diseases Society of America. All rights reserved.

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Sedaghat, A. R., Rastegar, D. A., OConnell, K. A., Dinoso, J. B., Wilke, C. O., & Blankson, J. N. (2009). T cell dynamics and the response to HAART in a cohort of HIV-1-infected elite suppressors. Clinical Infectious Diseases, 49(11), 1763–1766. https://doi.org/10.1086/648081

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