Successful in vitro fertilization pregnancy (IVF) after conservative management of endometrial cancer

Abstract

Objective: To report a successful IVF pregnancy in a couple after conservative treatment of endometrial cancer. DesignDesign: Case report and literature review. SettingSetting: ASL città di Torino – SC PMA, Valdese dpt. Patient(s)s): A 32-year-old white woman. Main Outcome Measure(s)s): Successful pregnancy after conservative management of endometrial cancer. Intervention(s)s): Grade 1 endometrial adenocarcinoma diagnosed at hysteroscopy, followed by dilatation and curettage (D&C). On follow-up D&C, pathologic examination was normal after high-dose progesterone therapy. The patient subsequently underwent an IVF cycle with transfer of one embryo. Result(s)s): The patient delivered a baby boy with a vaginal delivery at 37 weeks of gestational age. She is currently undergoing follow-up, and hysterectomy and bilateral salpingo-oophorectomy have not yet been performed. Conclusion(s)s): In carefully chosen situations, deferring surgery in infertile patients with endometrial cancer may be a viable option permitting subsequent successful pregnancy. KEY WORDS: IVF, endometrial cancer, save fertility, pregnancy conservative management.