Acylated Iridoid Glycosides from Buddleja japonica hemsl

Abstract

Sixteen new acylated iridoid glycosides, called buddlejosides —A16, were isolated from Buddleja japonica hemsl., together with four known iridoid glycosides; 6-vanilloyl-ajugol, 6-feruloyl-ajugol, verbascoside A, and 6-0-[a-L-(4-0-feruloyl)-rhamnopyranosyl]-catalpol. Structures of the new compounds were determined on the basis of chemical and spectroscopic evidence. Buddlejosides \\\\\\\\1was an ajugol derivative acylated with monoterpenic acid, A2 was an sinuatol and A3—A16 were 6-rhamnopyranosyl-catalpol derivatives acylated with cinnamic acid derivative and acetic acid. © 1991, The Pharmaceutical Society of Japan. All rights reserved.