Abstract
Recently, we have read with great interest the article entitled “The association between polymorphisms in the leptin receptor (LEPR) gene and risk of breast cancer: a systematic review and pooled analysis” published online by Wang et al. (Breast Cancer Res Treat 136:231–239, 2012). This article suggests that the A allele of LEPR gene rs1137101 variant was low-penetrant risk factor for developing breast cancer. The result is encouraging. Nevertheless, several key issues are worth noticing.
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Wang, Y., Yang, H., Gao, H., & Wang, H. (2015, May 1). The association between LEPR Q223R polymorphisms and breast cancer risk. Breast Cancer Research and Treatment. Springer New York LLC. https://doi.org/10.1007/s10549-015-3375-6
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