EFFECT OF COLLAPLUG® ON THE HEALING OF EXTRACTION SOCKETS IN PATIENTS UNDER ORAL ANTICOAGULANT THERAPY (CLINICAL STUDY)

Abstract

Introduction: Dentists perform a variety of surgical procedures frequently requiring the need for a hemostatic agent, in cases where oralanticoagulants are used. Most cases of postoperative bleeding are easily treated with local measures such as packing with a haemostatic dressing,suturing and pressure.Objectives: We aimed to evaluate the efficacy of Collaplug® in minimizing postoperative bleeding and pain following tooth extraction in patientsunder oral anticoagulant therapy.Materials and methods: A prospective study was conducted on a total of 40 adult patients under oral anticoagulant therapy, who needed toothextraction. Patients were divided equally into two groups, each group consisting of 20 patients. Group A (Study group): the extraction of the toothwas followed by the application of Collaplug® prior to suturing of the socket. Group B (Control group): the extraction of the tooth was followed bysuturing only.Results: A total of 40 patients 21 female (52%) and 19 (48%) male, aged between 30 and 60 years were included in the present study. All patientsunderwent simple tooth extraction. In the study group: there was a clinical significance in cessation of bleeding 2 hours and 6 hours after extractionthan the control group. All patients of study and control groups had their international normalized ratio (INR)Conclusion:The study concluded that Collaplug® is an effective local hemostatic material following minor oral surgery in patients under oral anticoagulanttherapy, also shows acceleration of soft tissue healing and reduce postoperative pain.