Malignant ossifying fibromyxoid tumor of the tongue: Case report and review of the literature

8Citations
Citations of this article
15Readers
Mendeley users who have this article in their library.

Abstract

Ossifying fibromyxoid tumor (OFMT) is a rare mesenchymal neoplasm that arises in subcutaneous tissue, with that in the oral cavity extremely rare. We present a case of malignant OFMT in the tongue. A 26-year-old male noticed a painless mass in the tongue, which was extracted at a general hospital. Four years later, the tumor recurred and was resected at our department. Histologically, the recurrent tumor was composed of the closely packed cells positive for vimentin and S-100 proliferating in a nodular fashion. It showed high cellularity and mitotic activity. In the primary tumor, some tumor cells were arranged in a diffuse or cord-like manner within an abundant fibromyxoid matrix, along with a small amount of metaplastic ossification, corresponding with the histopathological characteristic of OFMT. Accordingly, a diagnosis of malignant OFMT arising in typical OFMT was established. This is the first reported case of malignant OFMT in the tongue. Long-term follow-up is needed for confirmation of prognosis and biological behavior. © 2013 Ohta et al.; licensee BioMed Central Ltd.

Cite

CITATION STYLE

APA

Ohta, K., Taki, M., Ogawa, I., Ono, S., Mizuta, K., Fujimoto, S., … Kamata, N. (2013). Malignant ossifying fibromyxoid tumor of the tongue: Case report and review of the literature. Head and Face Medicine, 9(1). https://doi.org/10.1186/1746-160X-9-16

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free