Abstract
Novel substituted chromenopyridones ( 3a – j and 6a – d ) were synthesized and evaluated in vitro for the cytotoxic activity against various human cancer cell lines such as prostate (PC-3), breast (MCF-7), CNS (IMR-32), cervix (Hela), and liver (Hep-G2). preliminary cytotoxic screening showed that all the compounds possess a good to moderate inhibitory activity against various cancer cell lines. Particularly, compound 6b bearing allyl moiety displayed a significant cytotoxic potential in comparison to standard drugs.
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CITATION STYLE
Singh, B., Sharma, V., Singh, G., Kumar, R., Arora, S., & Ishar, M. P. S. (2013). Synthesis and In Vitro Cytotoxic Activity of Chromenopyridones. International Journal of Medicinal Chemistry, 2013, 1–7. https://doi.org/10.1155/2013/984329
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