Efficient transformations of aldehydes and ketones into one-carbon homologated carboxylic acids

Abstract

Peterson olefination of aldehydes and ketones with trimethylsilyl(methoxy)(benzotriazol-1-yl)methyl anion 6 afforded 1-(benzotriazol-1-yl)-1-methoxyalk-1-enes 7 which were treated without isolation with zinc bromide and hydrochloric acid, to yield the corresponding one-carbon homologated carboxylic acids 4 in good overall yields.