Variation of class I HLA antigen expression among platelet density cohorts: A possible index of platelet age?

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Abstract

Platelet alloantigens and other surface markers were studied in platelet cohorts of different mean denstiy, using monoclonal and polyclonal probes. High density (HD) platelets expressed 12% more P1(A1) molecules (46,942) than low density (LD) platelets ((41,892). However, LD platelets carried 42% more HLA-A2 molecules (6,267 ± 184) than HD platelets (4,406 ± 232) (P

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Pereira, J., Cretney, C., & Aster, R. H. (1988). Variation of class I HLA antigen expression among platelet density cohorts: A possible index of platelet age? Blood, 71(2), 516–519. https://doi.org/10.1182/blood.v71.2.516.516

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