Determination of probiotic potential and anticancer activity of lactobacillus isolated from cheese and yogurt

Abstract

In this study, microorganism was isolated from cheese and yogurt, cultured on specific culture media, then recognized molecularly through 16S rDNA f quality sequencing. The supernatant of Lactobacillus strains contained probiotic activity such as anticancer effects against cancer cell lines such as HeLa, RD and normal cell line (REF)cells and antibacterial. The cytotoxicity effects were assessed by MTT stain and apoptosis in mitochondria. The supernatant showed had anticancer activity against the tested cell lines (P< 0.05) with no significant cytotoxic effects against normal cell line.