Primary cutaneous marginal-zone lymphoma

Abstract

Primary cutaneous B cell lymphomas (PCBCL) are the second most common type of primary cutaneous lymphoma. The three main types of PCBCL are primary cutaneous marginal-zone lymphoma (PCMZL), primary cutaneous follicle-center lymphoma, and primary cutaneous diffuse large B-cell lymphoma, leg type. PCMZL has an indolent course with a five-year survival rate approaching 99%. Lesions most often present on the trunk or arm as erythematous-to-violaceous papules, plaques, or nodules. Approximately one-half of patients have solitary skin lesions. Treatment options include surgery, radiation, and topical, intralesional or systemic therapy. We present the case of a 33-yearold Hispanic woman with firm, pruritic, pink papules on the forehead and cheeks, who was diagnosed with PCMZL.