Efficient synthesis of functionalized organozinc compounds by the direct insertion of zinc into organic iodides and bromides

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Abstract

(Chemical Equation Presented) Insider dealing: A wide range of poly-functional (hetero)aromatic and aliphatic zinc reagents can be easily prepared in THF. The compounds are formed by a Zn insertion reaction mediated by the addition of LiCl (see scheme; All = allyl). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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Krasovskiy, A., Malakhov, V., Gavryushin, A., & Knochel, P. (2006). Efficient synthesis of functionalized organozinc compounds by the direct insertion of zinc into organic iodides and bromides. Angewandte Chemie - International Edition, 45(36), 6040–6044. https://doi.org/10.1002/anie.200601450

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