CD4 cell count and viral load count association and its joint risk factors among adult TB/HIV co-infected patients: a retrospective follow-up study

Abstract

Objective: The aim of this study was to determine CD4 cell count and viral load count association and its joint clinical risk factors among adult TB/HIV co-infected patients. The purpose of this research was leads to contribute improved planning and execution of screening programs, regular follow-ups, and prevention measures. Result: The baseline variability for viral load () was higher than CD4 cell (819.797). Furthermore, the correlation matrix (R) shows that the baseline subject-specific CD4 cell and viral load were negatively correlated (− 0.). There was also a negative relationship between the subject-specific change CD4 cell and baseline viral load (-), subject-specific baseline CD4 cell, and the patient-specific change of viral load (-0.6513), longitudinal trajectory (association of evolution) for the two random slopes -0.9413). Then, there was very strong negative relationship between subject-specific change CD4 cell and viral load over time. Visit time, white blood cell, good and fair) adherence, hemoglobin ≥ 11 g/dl, baseline CD4 cell ≥ 200 cells/mm3, and baseline viral load < 10,000 copies/mLhematocritand monocytes of patients were a joint determinates for viral load and CD4 cell, respectively.