Evaluation of a Novel Cisplatin Poloxamer Gel Formulation in the Treatment of Incompletely Excised Soft-Tissue Sarcomas: 42 Dogs

Abstract

Soft-tissue sarcomas are a group of skin tumours that are prone to local recurrence if not adequately surgically removed. This study describes a group of dogs in which a novel formulation of a chemotherapy agent (cisplatin) was injected into marginally excised tumour beds, in an attempt to reduce local recurrence rates. The results of this study help inform the future use of this drug and potentially lead to further investigative avenues for the use of these new compounds (poloxamers) in veterinary oncology.