Absence of linkage between chromosome 21 loci and familial amyotrophic lateral sclerosis

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Abstract

Familial amyotrophic lateral sclerosis (FALS) has recently been shown to be linked to chromosome 21 markers in a subset of families. However, we were unable to show linkage between FALS and chromosome 21 markers which flank the putative FALS locus in UK families.

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King, A., Houlden, H., Hardy, J., Lane, R., Chancellor, A., & De Belleroche, J. (1993). Absence of linkage between chromosome 21 loci and familial amyotrophic lateral sclerosis. Journal of Medical Genetics, 30(4), 318. https://doi.org/10.1136/jmg.30.4.318

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