Imipenem but not meropenem induces convulsions in DBA/2 mice, unrelated to cerebrospinal fluid concentrations

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Abstract

Imipenem and meropenem CSF diffusion was comparable in DBA/2 mice but only imipenem induced convulsions, not related to CSF concentration. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

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Dupuis, A., Pariat, C., Courtois, P., Couet, W., & Bouquet, S. (2000). Imipenem but not meropenem induces convulsions in DBA/2 mice, unrelated to cerebrospinal fluid concentrations. Fundamental and Clinical Pharmacology, 14(2), 163–165. https://doi.org/10.1111/j.1472-8206.2000.tb00406.x

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