Envolvimento cardíaco na lipodistrofia total generalizada (Síndrome de Berardinelli-Seip)

Abstract

Total generalized lipodystrophy (Berardinelli-Seip Syndrome) is a rare hereditary disease characterized by insulin-resistant diabetes mellitus and a small quantity of adipose tissue and is of unknown origin. Common cardiovascular alterations related to this syndrome are cardiac hypertrophy and arterial hypertension. This article reports a case of Berardinelli-Seip syndrome and reviews the literature with special emphasis on the cardiovascular manifestations of this syndrome.