Rapidly fatal acanthamoeba encephalitis and treatment of cryoglobulinemia

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Abstract

We describe a 66-year-old woman with therapy-refractory cryoglobulinemia treated with rituximab, plasmapheresis, and steroids; a case of fatal meningoencephalitis caused by Acanthamoeba spp. then developed. Such infections are rare and show an unusually rapid course (possibly related to rituximab).

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Meersseman, W., Lagrou, K., Sciot, R., De Jonckheere, J., Haberler, C., Walochnik, J., … Van Wijngaerden, E. (2007). Rapidly fatal acanthamoeba encephalitis and treatment of cryoglobulinemia. Emerging Infectious Diseases, 13(3), 469–471. https://doi.org/10.3201/eid1303.061001

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