Fungal agents in different anatomical sites in Public Health Services in Cuiabá, state of Mato Grosso, Brazil

  • Araújo S
  • Fontes C
  • Leite Júnior D
  • et al.
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Abstract

INTRODUCTION: A contribution to the regional epidemiological profile of the most common fungal agents in Public Health Services in Cuiabá, state of Mato Grosso, including university hospitals and polyclinics. METHODS: Clinical specimens (n = 1,496) from 1,078 patients were collected, submitted to direct mycological exam (potash or stick tape method) and cultured in specific mediums. Dermatophytic and non-dermatophytic agents were identified according to micromorphology (Ridell technique). RESULTS: The majority of the 1,496 specimens were skin (n = 985) and nail exams (n = 472). Of the 800 positive cultures, 246 (30.8%) corresponded to dermatophytes and 336 (42%) to yeasts of the genus Candida, 190 (23.7%) to other yeasts, 27 (3.4%) to non-dermatophytic filamentous fungi and one (0.1%) the agent of subcutaneous mycosis. Lesions considered primary occurred in greater numbers (59.5%) than recurrent lesions (37.4%), with a greater concentration of positivity occurring on the arms and legs. CONCLUSIONS: Comorbidities, allergies and diabetes mellitus were conditions associated with greater positivity in direct mycological exams and cultures. Positive culture was considered a definitive diagnosis of fungal infection and confirmed 47.8% of diagnostic hypotheses.INTRODUÇÃO: Contribuição sobre o perfil epidemiológico regional referente aos agentes fúngicos mais freqüentes nos Serviços de Saúde Pública em Cuiabá-MT, incluindo policlínicas e hospitais universitários. MÉTODOS: Foram examinados 1.496 espécimes clínicos colhidos a partir de 1.078 pacientes, os quais foram submetidos ao exame direto (potassa e/ou fita gomada) e cultivos em meios específicos. Os agentes foram identificados segundo micromorfologia (técnica de Ridell). RESULTADOS: Os 1.496 espécimes foram relacionados na maioria a exames de pele (n = 985), e unhas (n = 472). Dos 800 cultivos positivos, 246 (30,8%) corresponderam a dermatófitos, 336 (42%) a leveduras do gênero Candida, 190 (23,7%) a outras leveduras, 27 (3,4%) a fungos filamentosos não dermatofíticos e um (0,1%) a agente de micoses subcutâneas. Lesões consideradas primárias compareceram em maior número (59,5%), comparadas as recidivantes (37,4%). Foi observada maior positividade em membros inferiores e superiores. CONCLUSÕES: Co-morbidades, quadros alérgicos e diabetes mellitus representaram condições associadas à maior positividade em exames micológicos diretos e cultivos. O cultivo positivo foi considerado como diagnóstico definitivo de infecção fúngica, e confirmou 47,8% de hipóteses diagnósticas.

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APA

Araújo, S. M. de, Fontes, C. J. F., Leite Júnior, D. P., & Hahn, R. C. (2012). Fungal agents in different anatomical sites in Public Health Services in Cuiabá, state of Mato Grosso, Brazil. Revista Do Instituto de Medicina Tropical de São Paulo, 54(1), 5–10. https://doi.org/10.1590/s0036-46652012000100002

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