The pyrene excimer label (2) has been incorporated into the adjacent residue to the binding site of anti-ATP DNA aptamer. The fluorescent aptamer exhibited the specific fluorescence signal only in the presence of ATP.
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Ohtani, Y., Yamana, K., & Nakano, H. (2002). Molecular sensing by pyrene excimer signal of fluorescent DNA aptamer. Nucleic Acids Research. Supplement (2001), (2), 169–170. https://doi.org/10.1093/nass/2.1.169