Low Vitamin D Levels Increase the Risk of Early Onset Neonatal Sepsis

Abstract

Objective: To identify the association between maternal and umbilical cord vitamin D levels with suspects of Early- Onset of Neonatal Sepsis (EONS) in newborns from mothers with Preterm Premature Rupture of Membranes (PPROM). Methods: This is a retrospective cohort study conducted from January 2017 to Augusts 2018. Data was taken consecutively from medical records and previous study data at Dr. Cipto Mangunkusumo and Persahabatan Hospital, Jakarta. Results: From total of 72 infants from mothers with PPROM, 22 infants (31%) were EONS-suspected and 50 infants (69%) were not EONS-suspected. There was a significant association between maternal and umbilical cord vitamin D levels with EONS. Conclusions: There was a significant association between maternal and umbilical cord vitamin D levels with EONS.