Abstract
Catalytic methods for the synthesis of previously unknown 2,9-disubstituted 3bR*,7aR*,10bR*,14aR*-cis-14c,14d-perhydro-2,3a,7b,9,10a,14b-hexaazadibenzotetracenes have been developed. The structures were established by 1D (1H,13C) and 2D (COSY, HSQC, HMBC) NMR spectroscopy, MALDI TOF/TOF mass spectrometry, and X-ray diffraction analysis. Primary screening of the synthesized perhydro hexaazadibenzotetracenes for antitumor activity was carried out.
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CITATION STYLE
Rakhimova, E. B., Kirsanov, V. Y., Tret’yakova, E. V., Khalilov, L. M., Ibragimov, A. G., Dzhemileva, L. U., … Dzhemilev, U. M. (2020). Synthesis, structure, and antitumor activity of 2,9-disubstituted perhydro 2,3a,7b,9,10a,14b-hexaazadibenzotetracenes. RSC Advances, 10(36), 21039–21048. https://doi.org/10.1039/d0ra03209c
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