Treatment of systemic lupus erythematosus

Abstract

Systemic lupus erythematosus should be suspected in individuals with one or more classic symptoms. Diagnosis is made clinically and supported by serology. Reducing sun exposure is central to the management of lupus. Hydroxychloroquine is first-line treatment unless contraindicated and is useful in almost all manifestations of lupus. Other treatments are titrated against type and severity of organ involvement. Monoclonal antibodies have a limited role in the management of lupus.