Synthesis of new phenylpyrrolizinones via a Mannich reaction

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Abstract

The synthesis of 2-methylidene-3-phenyl-2,3-dihydro-1H-pyrrolizin-I-one 2d and subsequent Michael additions to this α,β-unsaturated ketone is described.

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Sonnet, P., Miel, H., Guillon, J., Dallemagne, P., & Rault, S. (1999). Synthesis of new phenylpyrrolizinones via a Mannich reaction. Heterocyclic Communications, 5(1), 25–26. https://doi.org/10.1515/HC.1999.5.1.25

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