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Modelling and deciphering tumour metabolism in CRISPR screens

Nature Reviews Cancer
DOI: 10.1038/s41568-024-00758-8
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Abstract

Cell culture-based CRISPR screens have become instrumental in functionally annotating the human genome and identifying cancer dependencies. However, standard culture conditions poorly recapitulate the metabolic environments of tissues and organs. Modelling tumour-associated metabolic conditions opens new opportunities for cancer biology and therapeutic discovery.

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APA

Zuber, J., & Palm, W. (2025, January 1). Modelling and deciphering tumour metabolism in CRISPR screens. Nature Reviews Cancer. Nature Research. https://doi.org/10.1038/s41568-024-00758-8

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