Study of the anti-inflammatory activity of flavonic extract of globularia alypum L.

Abstract

Globularia alypum L. of the family Globulariaceae is widely used in traditional medicine for its antiinflammatory activity. The aim of this study is to evaluate the anti-inflammatory activity of flavonic extract (butanol fraction) of globularia alypum against carrageenan induced paw-oedema in mice. The results have shown that the dose of 0.3 g/ml of butanol fraction present the most significant activity (33.01%) compared with reference product aspirine (39.76%) at dose of 2 mg/ml.