Prognostic role and relationship of thyroid dysfunction and lipid profile in hospitalized heart failure patients

Abstract

Background: Thyroid dysfunction might have a negative impact on the prognosis of patients with heart failure (HF) and affect the lipid metabolism. The aim of our study was to investigate the prognostic role of thyroid dysfunction and its relationship with lipid profile in hospitalized HF patients. Hypothesis: Thyroid dysfunction strongly correlates with prognosis of HF patients and combination with lipid profile improves the prognostic value. Methods: We performed a single-center retrospective cohort study including hospitalized HF patients between March 2009 and June 2018. Results: Among enrolled 3733 patients, low fT3 (hazard ratio [HR] 1.33; 95% CI: 1.15–1.54; p