Preparation, structural, and optical features of two-dimensional cross-linked DNA/gold-nanoparticle conjugates

Abstract

The formation and the optical features of two-dimensional aggregates formed by DNA-directed immobilization and cross-linking of bifunctional DNA-gold nanoparticles at flat gold substrates are analyzed. The samples are structurally characterized by atomic force microscopy to evaluate the particle size, the particle densities, and the degree of aggregation. The optical characteristics determined by UV/visible measurements are correlated with the structural features observed. © Springer-Verlag 2006.