Development of P-spiro chiral aminophosphonium salts as a new class of versatile organic molecular catalyst

Abstract

A series of P-spiro chiral tetraaminophosphonium salts have been designed and synthesized as a new class of organic molecular catalysts, and their inherent abilities to exert four different, synthetically relevant asymmetric catalyses have been brought out through the unique molecular design on a single core structure, N4P+. Further, these catalyses have been applied to the development of various C-C, C-P, and C-N bondforming reactions, in which the remarkably high catalytic performances and Stereocontrolling abilities of the chiral tetraaminophosphonium salts have been successfully demonstrated.