Nano-particle assisted laser desorption/ionization (Nano-PALDI) mass spectrometry for detection of pesticide

Abstract

We detected pesticides by nano-particle assisted laser desorption/ionization mass spectrometry (Nano-PALDI MS). Several nanoparticles (NPs) by mixing aqueous solutions of 3d transition metal chlorides (MCl2·nH2O) and (3-aminopropyl) triethoxysilane were synthesized to explore the optimum NPs for detection of pesticides by Nano-PALDI MS. The prepared NPs were examined by X-ray diffraction, transmission electron microscope, and Fourier transform infrared spectroscopy. The synthesized NPs were surrounded by amorphous SiO2 and possessed amino and hydroxyl groups on NPs surface. The number-average diameter of the NPs was determined to be about 3 to 5 nm. The NPs could assist ionization of pesticides in MS. We selected the suitable NPs to detect pesticide by statistical method. The copper oxide-based Nano-PALDI MS could be time lapse analysis of the pesticides as environmental pollutant from paddy field.