The SYBR green I malaria drug sensitivity assay: Performance in low parasitemia samples

Abstract

Validation of the sensitivity of the SYBR Green I in vitro test against an enzyme-linked immunosorbent assay (ELISA)-based drug sensitivity assay. Our results suggest that the SYBR Green I assay is a fast and inexpensive malaria drug screening assay for laboratory use. However, because of its lack of sensitivity in whole blood samples its usefulness for testing clinical samples may be limited. Copyright © 2010 by The American Society of Tropical Medicine and Hygiene.